Current Grants

“Multi‐Site Communication in the Brain” (Collaborative Research Center 936)

Co- Principal Investigators (Subproject C5): Prof. Dr. Alexander Münchau and Prof. Dr. Christine Klein
Funding Agency: German Research Foundation (DFG)
Funding period: 2011-2023
Amount: 1,245,800 €

“MDS Gene Tool“

Principal Investigator: Prof. Dr. Christine Klein
Funding agency: The International Parkinson and Movement Disorder Society
Funding period: 2014-2022
Amount: 584,400 €

“Research Unit FOR2488: Reduced penetrance in hereditary movement disorders: Elucidating mechanisms of endogenous disease protection – Protect Move”

Principal Investigator: Prof. Dr. Christine Klein
Funding agency: Deutsche Forschungsgemeinschaft
Funding period: 2017-2022
Amount: 7,967,325 €

“Elucidating the Interaction between Mitochondria and Lipids in Parkinson´s Disease”

Principal Investigator: Melissa Vos, PhD
Funding agency: Else Kröner Fresenius Stiftung
Funding period: 2017-2021
Amount: 294,030 €

“Tiefe Hirnstimulation als effektives Behandlungsverfahren bei Patienten mit einer schweren genetisch bedingten Bewegungsstörung auf den Philippinen”

Principal Investigator: Prof. Dr. Norbert Brüggemann
Funding agency: Else Kröner Fresenius Stiftung
Funding period: 2017-2021
Amount: 371,815 €

“Defining clinical and neurophysiological markers of effective deep brain stimulation treatment in dystonia”

Principal Investigator: Anne Weißbach, MD
Funding agency: Else Kröner Fresenius Stiftung
Funding period: 2018-2021
Amount: 202,497 €

“The use of vitamin K2 in patients with mitochondrial Parkinson´s disease”

Principal Investigator: Jannik Prasuhn, MD
Funding agency: Parkinson´s Foundation
Funding period: 2018-2021
Amount: 200,000 USD

“Variable expressivity in SGCE-associated myoclonus dystonia”

Principal Investigator: Karen Grütz, PhD
Funding agency: Dystonia Medical Research Foundation
Funding period: 2019-2021
Amount: 74,540 USD

“LIPAD”

Principal Investigator: Prof. Dr. Christine Klein and Prof. Dr. Meike Kasten
Funding agency: CENTOGENE AG
Funding period: 2019-2022
Amount: 1,000,000 €

“Identification of new modifier genes of TAF1 protein expression”

Principal Investigator: Philip Seibler, PhD
Funding agency: Collaborative Center for XDP at Massachusetts General Hospital
Funding period: 2019-2021
Amount: 110,000 USD

“Deep characterization of mitochondrial DNA to discover penetrance modifiers of monogenetic Parkinson´s disease”

Principal Investigator: Joanne Trinh, PhD
Funding agency: Peter und Traudl Engelhorn Stiftung
Funding period: 2020-2021
Amount: 145,800 €

“The global monogenic Parkinson´s disease cohort – establishing a comprehensive research and clinical trial-ready resource”

Principal Investigator: Prof. Dr. Christine Klein
Funding agency: The Michael J. Fox Foundation for Parkinson´s Research
Funding period: 2020-2021
Amount: 162,454.83 USD

“Cerebello-neokortikale Netzwerkveränderungen bei Dystoniepatienten – Die monogenetische Myoklonus-dystonie als cerebelläre Modelerkrankung”

Principal Investigator: Anne Weißbach, MD
Funding agency: Deutsche Forschungsgemeinschaft
Funding period: 2020-2023
Amount: 436,279 €

“Identifizierung von neuen genetischen Ursachen von dystonien durch Hochdurchsatz-Sequenzierung”

Principal Investigator: Prof. Dr. Christine Klein
Funding agency: Deutsche Forschungsgemeinschaft
Funding period: 2020-2023
Amount: 24,200 €

“Identifizierung von neuen genetischen Ursachen von dystonien durch Hochdurchsatz-Sequenzierung”

Principal Investigator: Prof. Dr. Katja Lohmann
Funding agency: Deutsche Forschungsgemeinschaft
Funding period: 2020-2023
Amount: 143,200 €

“Investigation of age-at-onset genetic modifier loci in LRRK2 parkinsonism”

Principal Investigator: Joanne Trinh, PhD
Funding agency: Else Kröner Fresenius Stiftung
Funding period: 2020-2023
Amount: 267,850 €

“Global Parkinson´s Genetics Program (GP2) – 2021 Working Group Lead”

Principal Investigator: Christine Klein
Funding agency: The Michael J. Fox Foundation  
Funding period: 2021
Amount: US$ 25,000

“Global Parkinson´s Genetics Program (GP2) – 2021 Working Group Lead”

Principal Investigator: Katja Lohmann
Funding agency: The Michael J. Fox Foundation  
Funding period: 2021
Amount: US$ 15,000

“Enrollment of subjects into the Dystonia Coalition Projects”

Principal Investigator: Christine Klein
Funding agency: Dystonia Coalition
Funding period: 2011–2023
Amount: € 100,000

“The Parkinson´s Progression Markers Initiative (PPMI)”

Principal Investigator: Christine Klein
Funding agency: The Michael J. Fox Foundation  
Funding period: 2020-2024
Amount: US$ 1,000,000

“Global Parkinson´s Genetic Program (GP2) Working Groups: Monogenic PD Hub, Monogenic Portal Development, Monogenic Sample Prioritization & Monogenic Data Analysis”; 18802

Principal Investigator: Christine Klein
Funding agency: The Michael J. Fox Foundation  
Funding period: 2020-2021
Amount: US$ 1,494,513.31

“Master Services Agreement: Biomaterials and clinical data of Parkinson disease (PD) patients with mutations in Parkin, PINK1, and GBA, matched, mutation negative PD patients, and unaffected controls”

Principal Investigator: Christine Klein
Funding agency: The Michael J. Fox Foundation  
Funding period: 2020-2022
Amount: US$ 298,434.20

“B-Fast”

Principal Investigator: Christine Klein
Funding agency: Charité Berlin (DLR)
Funding period: 2020-2021
Amount: € 408,079.86

“The neuroprotective role of retromer”

Principal Investigator: Philip Seibler
Funding agency: Retromer Therapeutics
Funding period: 2021-2023
Amount: € 479,318