Marija Dulović Mahlow, MD, PhD

Postdoctoral Researcher

Postdoctoral Researcher (Genetics of Rare Diseases; Drosophila Models of Neurodegeneration)

Functional characterization of novel disease-causing mutations and studying the underlying mechanisms, which are causative for movement disorders

Education:

2000-2008 Medical studies; School of Medicine, University of Belgrade (Serbia)
Obtained medical degree (M.D.; 9.06/10.00)

2009 Six-months clinical internship; Clinical Center of Serbia (Belgrade, Serbia)
Obtained medical license

2010-2015 Doctoral thesis in Molecular medicine; University of Belgrade (Serbia), Institute of Medical and Clinical Biochemistry, School of Medicine (Director: Prof. Dr. I. Marković) and Clinical Center of Serbia, Department of neurodegenerative diseases (Director: Prof. Dr. V. S. Kostic)
Ph.D. thesis: “The role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro”
Obtained Ph.D. degree (Ph.D.; 9.60/10.00)

2012-present Specialization in Laboratory Medicine; School of Medicine, University of Belgrade (Serbia)

Scientific training & Professional Experience:

2005–2006 Medical student researcher; Department of Psychiatry, Clinical Centre of Serbia, Belgrade (Serbia)
Project: “Is there any difference in IQ among types of psychiatric disorders?”

2006–2008 Medical student researcher;  Institute of Medical and Clinical Biochemistry, School of Medicine, University of Belgrade (Serbia)
Project: “Protective role of endogenous nucleosides on primary rat astrocytes in energy depleting conditions”

2009–2011 Clinical researcher;  Institute of Medical and Clinical Biochemistry, School of Medicine, University of Belgrade (Serbia) and Ministry of Education, Science and Technological Development, Belgrade (Serbia)
Project: “Molecular mechanisms of cell death regulation at physiological and pathological conditions”

2011–2018 Clinical researcher;  Institute of Medical and Clinical Biochemistry, School of Medicine, University of Belgrade (Serbia)
Project: “Modulation of intracellularenergy balance-controlling signaling pathways in therapy of cancer andneuro-immuno-endocrine disorders”

2011–2018 Teaching Assistant;  Institute of Medical and Clinical Biochemistry, School of Medicine, University of Belgrade (Serbia)
Subject: Medical and Clinical Biochemistry
Education in Serbian and English language

2016–present Postdoctoral Researcher; Institute of Neurogenetics, University of Luebeck (Germany)

Awards:

2011 The Best Poster Presenter Award, 5th Conference of the Serbian Society of Neuroscience, Kopaonik (Serbia)
2011 Travel grant, ISN-ESN 23rd Biennial meeting, Athens (Greece)
2011 Travel grant, SiNAPSA Neuroscience Conference ‘11, Ljubljana (Slovenia)
2011 Travel grant, DAAD Workshop: Current Methods in Neurosciences, Kotor (Montenegro)
2011 Travel grant, ICGEB theoretical Course: Mouse Genetics; Models for Human Diseases, Trieste (Italy)
2012 Travel grant, 44th International Danube Neurology Symposium, Szeged (Hungary)
2012 Travel grant, 8th FENS Forum of Neuroscience, Barcelona (Spain)
2012 The Best Abstract Award (under supervision of Dulovic M, MD PhD), 23rd European Student's Conference, Charite, Berlin, Germany
2013 The Best Abstract Award (under supervision of Dulovic M, MD PhD), 8th International Medical Students' Congress in Novi Sad (Serbia)
2013 Travel grant, FENS Regional Meeting, Prague (Czech Republic)
2013 Travel grant, The EU FP7 Glowbrain Workshop: Application of biomaterials and in vivo imaging in stem cell research, Zagreb (Croatia)
2014 Travel grant, 27th ECNP Congress, Berlin (Germany)
2014 Travel grant, COST Action BM1001: Tenascins and ECM Modulation in Plasticity and Neuroinflammation, Belgrade (Serbia)
2015 6-month Scholarship for Young Neuroscientists from the Foundation “Risto Bokonjic”, Munich (Germany)
2016 2-month Universitätsklinikum SH Stipendium, Luebeck (Germany)
2016 1-year scholarship from the DAAD, Bonn (Germany)

  1. Wittke C, Petkovic S, Dobricic V, Schaake S, MDS‐endorsed PSP Study Group, Respondek G, Weissbach A, Madoev H, Trinh J, Vollstedt EJ, Kuhnke N, Lohmann K, Dulovic Mahlow M, Marras C, König IR, Stamelou M, Bonifati V, Lill CM, Kasten M, Huppertz HJ, Höglinger G, Klein C. Genotype-Phenotype Relations for the Atypical Parkinsonism Genes: MDSGene Systematic Review. Movement Disorders : official Journal of The Movement Disorder Society 2021;7:1499-1510.
  2. Kasten M, Hartmann C, Hampf J, Schaake S, Westenberger A, Vollstedt EJ, Balck A, Domingo A, Vulinovic F, Dulovic M, Zorn I, Madoev H, Zehnle H, Lembeck CM, Schawe L, Reginold J, Huang J, König IR, Bertram L, Marras C, Lohmann K, Lill CM, Klein C. Genotype-Phenotype Relations for the Parkinson's Disease Genes Parkin, PINK1, DJ1: MDSGene Systematic Review. Mov Disord 2021;5:730-741.
  3. Kasten M, Hartmann C, Hampf J, Schaake S, Westenberger A, Vollstedt EJ, Balck A, Domingo A, Vulinovic F, Dulovic M, Zorn I, Madoev H, Zehnle H, Lembeck CM, Schawe L, Reginold J, Huang J, König IR, Bertram L, Marras C, Lohmann K, Lill CM, Klein C. Genotype-Phenotype Relations for the Parkinson's Disease Genes Parkin, PINK1, DJ1: MDSGene Systematic Review. Mov Disord 2021;5:730-741.
  4. Dulovic M, Vos M. Sleep dysfunction in Parkinson's disease: Novel molecular mechanism and implications for therapy. Mov Disord 2018;10:1558-1559.
  5. Seibler P, Burbulla LF, Dulovic M, Zittel S, Heine J, Schmidt T, Rudolph F, Westenberger A, Rakovic A, Münchau A, Krainc D, Klein C. Iron overload is accompanied by mitochondrial and lysosomal dysfunction in WDR45 mutant cells. Brain 2018;10:3052-3064.
  6. Dulovic M, Schäffer E, Leypoldt F, Balck A, Schaake S, Hinrichs F, Kirchner H, Brüggemann N, Berg D, Lohmann K. A Klinefelter patient with an additional mitochondrial mutation: Implications for genotype-driven treatment and mitochondrial mutational load in different tissues and family members. Parkinsonism Relat Disord 2018:116-118.
  7. Seong E, Insolera R, Dulovic M, Kamsteeg EJ, Trinh J, Brüggemann N, Sandford E, Li S, Ozel AB, Li JZ, Jewett T, Kievit AJA, Münchau A, Shakkottai V, Klein C, Collins CA, Lohmann K, van de Warrenburg BP, Burmeister M. Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects. Ann Neurol 2018;6:1075-1088.