Guest Speakers & Group Meetings

Guest Speakers

Date YYYY/MM/DD Guest Speaker
2023/12/12 Guest speaker: Prof. and GEoPD president Katerina Markoupolou Title: DBS and Genetics of Parkinson’s Disease – A Window into Disease Pathophysiology
2024/05/13 Presentations for special guests: 1. Introduction - (Dr. Christine Klein) 2. Introduction to the MDSGene database (with LRRK2 as an example) - (Mirja Thomsen) 3. Genetic and environmental LRRK2 modifiers - (Dr. Joanne Trinh, Dr. Theresa Lueth) 4. Rostock International Parkinson's Disease Study (ROPAD) - (Dr. Ana Westenberger) 5. Genetic basis of age-related penetrance in XDP - (Shela Algodon) 6. Modelling disease: patient-derived iPSC-based models of PD - (Dr. Linn Streubel-Gallasch)
2024/05/28 Guest speaker: Dr. Justin Lee from the Institute for Basic Science, South Korea Title: Astrocytic hemoglobin is a H2O2-decomposing peroxidase and a therapeutic target for Alzheimer’s disease and ischemic stroke
2024/08/13 Guest speaker: Dr. Björn-Hergen Laabs, Institute of Medical Biometry and Statistics, University of Lübeck Title: Dos and don'ts in Excel when working with a statistician - A (self)-ironic summary
2024/08/22 Guest speaker: Dr. Zih-Hua Fang, GP2 - Lead Monogenic Data Analysis, German Center for Neurodegenerative Diseases Title: Ongoing work in the Global Parkinson's Genetics Program
2024/09/17 Guest speaker: Dr. Madiha Malik, Institute of Pharmacy, University of Kiel Title: Breath-taking Discoveries: Unveiling the Diagnostic Potential of Exhaled Breath Analysis in Clinical Settings

Group Meetings

Date YYYY/MM/DD Research section & presenter (Progress Report) Presentation title (Progress Report) Research section & presenter Paper & DOI (Journal Club)
2023/11/21 Applied Stem Cell Biology, Dr. Linn Streubel-Gallasch The retromer and seeding assay projects - Update - -
2023/11/28 Integrative Omics in Parkinson Disease, Carolin Gabbert Identifying the genetic cause in Norwegian families with Parkinson’s disease Integrative Omics in Parkinson Disease, Theresa Lüth A blood-based marker of mitochondrial DNA damage in Parkinson’s disease, 10.1126/scitranslmed.abo1557
2023/12/07 - - Genetics of Rare Diseases, Kaja Schröder De novo retinoic acid receptor beta (RARB) variant associated with microphthalmia and dystonia, 10.1016/j.ejmg.2023.104802
2024/01/09 Integrative Omics in Parkinson Disease, Dr. Joanne Trinh Overview of present and future projects in the Integrative Omics research group - -
2024/01/16 Genetics of Rare Diseases, Aida Diaw Tissue-specific imprinting of SGCE and expressional changes in dystonia - -
2024/01/23 - - Applied Stem Cell Biology, Dr. Linn Streubel-Gallasch Propagative α-synuclein seeds as serum biomarkers for synucleinopathy, 10.1038/s41591-023-02358-9
2024/02/06 Molecular Mechanisms of Movement Disorders, Arian Hach Progress on PRKN Exon 2 deletion project - -
2024/02/20 Translational Neurogenetics, Dr. Christine Klein Neurogenetics in the Clinic - -
2024/03/05 Applied Stem Cell Biology, Hannah Wimmerstedt Differentiation and Characterization of Astrocytes - -
2024/03/12 Genetics of Rare Diseases, Dr. Katja Lohmann Updates from the group - Molecular Genetics of Rare Diseases Integrative Omics in Parkinson Disease, Dr. Joanne Trinh A pathogenic variant in RAB32 causes autosomal dominant Parkinson’s disease and activates LRRK2 kinase, 10.1101/2024.01.17.24300927
2024/04/02 Integrative Omics in Parkinson Disease, Carolin Gabbert The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson's disease Translational Neurogenetics, Dr. Maria Leila Doquenia Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease, 10.1038/s41588-023-01584-8
2024/04/09 Molecular Mechanisms of Movement Disorders, Arian Hach Remaining Parkin function & later AAO in homozygous PRKNdelEx2 carriers - -
2024/04/16 Translational Neurogenetics, Dr. Cholpon Shambetova Report from Kyrgyzstan: Training and Progress in Building a New Cohort Molecular Mechanisms of Movement Disorders, Dr. Aleksandar Rakovic A mutational atlas for Parkin proteostasis, 10.1038/s41467-024-45829-4
2024/04/23 Applied Stem Cell Biology, Letizia Santinelli Investigation of the morphological and molecular effect of the phosphatase PTEN in primary murine Schwann cells Genetics of Rare Diseases, Dr. Katja Lohmann Dissecting genetic architecture of rare dystonia: genetic, molecular and clinical insights, 10.1136/jmg-2022-109099
2024/04/30 Integrative Omics in Parkinson Disease, Joshua Laß Mid-point seminar for PhD thesis Applied Stem Cell Biology, Dr. Linn Streubel-Gallasch MDS-ES FOCUSED WORKSHOP: Diagnostic and Progression Biomarkers in Parkinson’s Disease and Atypical Parkinsonism
2024/05/07 Genetics of Rare Diseases, Pin-Jui Kung Elevated TAOK1 Levels in Plasma-Derived Extracellular Vesicles: A Diagnostic Marker for Cognitive Decline in Parkinson’s Disease Dementia and Alzheimer’s Disease - -
2024/05/30 Functional Genetics of Movement Disorders, Dr. Ana Westenberger Rostock International Parkinson's Disease Study (ROPAD) - -
2024/06/06 Translational Neurogenetics, Dr. Christine Klein New biological classifications of Parkinson's disease - -
2024/06/13 Molecular Mechanisms of Movement Disorders, Kerstin Tanzer Progress Report on the DYT-TOR1A Project Translational Neurogenetics, Dr. Karen Grütz Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing, 10.1016/j.nbd.2023.106367
2024/06/25 Applied Stem Cell Biology, Dr. Linn Streubel-Gallasch Update: seed amplification assay and extracellular vesicle isolation - -
2024/07/04 - - Genetics of Rare Diseases, Lena Nothacker eIF2α phosphorylation evokes dystonia-like movements with D2-receptor and cholinergic origin and abnormal neuronal connectivity, 10.1101/2024.05.14.594240
2024/07/18 Integrative Omics in Parkinson Disease, André Fienemann Optical genome mapping and long-read sequencing of structural variants in Parkinson’s disease-related induced pluripotent stem cells - -
2024/07/23 Applied Stem Cell Biology, Dr. Philip Seibler Annual lab safety instructions Molecular Mechanisms of Movement Disorders, Arian Hach Plasma proteomics identify biomarkers predicting Parkinson’s disease up to 7 years before symptom onset, 10.1038/s41467-024-48961-3
2024/08/27 Genetics of Rare Diseases, Dr. Katja Lohmann Update of research section projects - -
2024/09/23 Integrative Omics in Parkinson Disease, Carolin Gabbert Gene-environment modifiers in Parkinson’s disease - -